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KMID : 0384320070280100748
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Korean Journal of Family Medicine
2007 Volume.28 No. 10 p.748 ~ p.753
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Smoking Status and Augmentation Index in Korean Male Subjects
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Woo Eui-Jeong
Lee Hong-Soo
Lee Sang-Wha
Shim Kyung-Won
Kim Soo-A
Oh Young-A
Lee Myoung-Jin
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Abstract
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Background: Smoking is a major risk factor of cardiovascular morbidity and mortality. Arterial stiffness has been identified as an important determinant of cardiovascular risk. Augmentation index is an indicator of arterial stiffness, which can be quantified noninvasively. The goal of this study was to assess the effect of current smoking status on augmentation index (AIx) in Korean male subjects.
Methods:A total of 70 males without clinical cardiovascular diseases were studied in this cross sectional study. AIx was measured in 35 current smokers and 35 nonsmokers by recording pressure waveforms using radial applanation tonometry in a SphygmoCor device.
Results: Augmentation index was significantly higher in the current smokers (19.4±12.9% vs. 9.7±12.8%; P＜0.05). A multiple regression model confirmed that smoking status was independently associated with arterial stiffness
(β=0.350, P＜0.001).
Conclusion: Current smoking is associated with increased augmentation index, which is a marker of ardiovascular disease. Further studies are required to investigate clinical applications of arterial stiffness.
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KEYWORD
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smoking, augmentation index, arterial stiffness
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